Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Prothrombin 
Descriptor Spanish:   Protrombina 
Descriptor Portuguese:   Protrombina 
Synonyms English:   Blood Coagulation Factor II
Coagulation Factor II
Differentiation Reversal Factor
Factor II
Factor II, Coagulation
Factor, Differentiation Reversal
II, Coagulation Factor  
Tree Number:   D08.622.709
Definition English:   A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia. 
Indexing Annotation English:   a blood coag factor; an enzyme precursor
Entry Combination - descr/qualif English:   Prothrombin/deficiency use Hypoprothrombinemias
See Related English:   Coagulants
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22270 
Unique Identifier:   D011516 

Occurrence in VHL: