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PREKALLIKREIN
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DeCS
Descriptor
English
:
Prekallikrein
Descriptor
Spanish
:
Precalicreína
Descriptor
Portuguese
:
Pré-Calicreína
Synonyms
English
:
Factor, Fletcher
Fletcher Factor
Kallikreinogen
Plasma Prokallikrein
Plasma Prokallikrein A
Prokallikrein A, Plasma
Prokallikrein, Plasma
Tree Number:
D08.622.658
D08.811.277.656.300.760.442.725
D08.811.277.656.959.350.442.725
D12.776.124.125.597.712
D12.776.811.243.658
D23.119.597.712
Definition
English
:
A
plasma
protein which is the precursor of kallikrein.
Plasma
that is deficient in
prekallikrein
has been found to be abnormal in
thromboplastin
formation, kinin generation, evolution of a
permeability
globulin, and plasmin formation. The absence of
prekallikrein
in
plasma
leads to Fletcher factor deficiency, a congenital
disease.
See Related
English
:
Coagulants
History Note
English
:
89(76); was see under KALLIKREINS 1976-88
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22264
Unique Identifier:
D011288
Occurrence in VHL
:
Similar:
DeCS