Search on: FIBRINOGEN 
Descriptors Found: 1
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Descriptor English:   Fibrinogen 
Descriptor Spanish:   Fibrinógeno 
Descriptor Portuguese:   Fibrinogênio 
Synonyms English:   Blood Coagulation Factor I
Coagulation Factor I
Factor I
Factor I, Coagulation
gamma Fibrinogen
Tree Number:   D12.776.124.050.250
Definition English:   Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. 
Indexing Annotation English:   a blood coag factor: do not confuse X ref FACTOR I with COMPLEMENT FACTOR I
Entry Combination - descr/qualif English:   Fibrinogen/deficiency use Afibrinogenemia
See Related English:   Coagulants
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22179 
Unique Identifier:   D005340 

Occurrence in VHL: