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DeCS
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Descriptor English:
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Complement Factor I
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Descriptor Spanish:
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Factor I de Complemento
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Descriptor Portuguese:
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Fator I do Complemento
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Synonyms English:
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C3b C4b Inactivator
C3b Inactivator
C3b-C4b Inactivator
C4b C3b INA
C4b-C3b Inactivator, Complement
C4b-C3b-INA
C4bC3bINA
Complement 3b Complement 4b Inactivator
Complement 3b-Complement 4b Inactivator
Complement C4b C3b Inactivator
Complement C4b-C3b Inactivator
Inactivator, C3b
Inactivator, C3b-C4b
Inactivator, Complement C4b-C3b
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Tree Number:
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D08.811.277.656.300.760.210
D08.811.277.656.959.350.210
D12.776.124.486.274.920.325.210
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Definition English:
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A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator. |
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Indexing Annotation English:
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do not confuse with FACTOR I see FIBRINOGEN
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Pharmacological Action:
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Complement Inactivating Agents
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History Note English:
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93; was FACTOR I, C 3B INACTIVATOR (NM) 1983-92
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Allowable Qualifiers English:
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Record Number:
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30774
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Unique Identifier:
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D017244
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Occurrence in VHL:
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Similar:
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DeCS
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