Search on: GELSOLIN 
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Descriptor English:   Gelsolin 
Descriptor Spanish:   Gelsolina 
Descriptor Portuguese:   Gelsolina 
Synonyms English:   Gelsolin Protein
Serum Actin Inhibitory Protein  
Tree Number:   D05.750.078.730.350
Definition English:   A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS. 
History Note English:   1994(1980) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   31448 
Unique Identifier:   D018260 

Occurrence in VHL: