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Descriptor English:   Apolipoprotein C-II 
Descriptor Spanish:   Apolipoproteína C-II 
Descriptor Portuguese:   Apolipoproteína C-II 
Synonyms English:   Apo C II
Apo C-II
Apolipoprotein C 2
Apolipoprotein C II
Apolipoprotein C-2
Apolipoprotein CII
Apoprotein C II
Apoprotein C-II  
Tree Number:   D10.532.091.400.750
Definition English:   A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB. 
See Related English:   Hyperlipoproteinemia Type I
History Note English:   2007; use APOLIPOPROTEIN C-II (NM) 1978-2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52263 
Unique Identifier:   D053304 

Occurrence in VHL: