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DeCS
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Descritor Inglês:
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Receptors, Death Domain
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Descritor Espanhol:
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Receptores de Muerte Celular
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Descritor Português:
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Receptores de Morte Celular
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Sinônimos Inglês:
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DR Family Receptors
Death Domain Receptors
Death Receptors
Receptors, DR Family
Receptors, Death Domain Family
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Categoria:
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D12.776.543.750.690
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Definição Inglês:
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A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES. |
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Relacionados Inglês:
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Receptors, Tumor Necrosis Factor
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Nota Histórica Inglês:
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2007
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Qualificadores Permitidos Inglês:
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Número do Registro:
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52336
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Identificador Único:
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D053218
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Ocorrência na BVS:
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Similar:
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DeCS
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