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Descriptor English:   Interferon beta-1a 
Descriptor Spanish:   Interferón beta-1a 
Descriptor Portuguese:   Interferon beta-1a 
Synonyms English:   Avonex
Avonex Pen
Interferon beta 1a
Rebif
beta 1a, Interferon
beta-1a, Interferon  
Tree Number:   D12.644.276.374.440.890.275.500
D12.776.467.374.440.890.275.500
D23.529.374.440.890.275.500
Definition English:   An interferon beta-1 subtype that has a methionine at position 1, a cysteine at position 17, and is glycosylated at position 80. It functions as an ANTI-VIRAL AGENT and IMMUNOMODULATOR and is used to manage the symptoms of RELAPSING-REMITTING MULTIPLE SCLEROSIS. 
Pharmacological Action:   Adjuvants, Immunologic
Antineoplastic Agents
Antiviral Agents
 
History Note English:   2016 (1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55969 
Unique Identifier:   D000068556 

Occurrence in VHL:
 

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