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INTERFERONS
Descriptors Found:
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DeCS
Descriptor
English
:
Interferons
Descriptor
Spanish
:
Interferones
Descriptor
Portuguese
:
Interferons
Synonyms
English
:
Interferon
Tree Number:
D12.644.276.374.440
D12.776.467.374.440
D23.529.374.440
Definition
English
:
Proteins
secreted by
vertebrate
cells in response to a wide variety of inducers. They confer resistance against many different
viruses
, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular
parasites
, enhance macrophage and
granulocyte
phagocytosis
, augment natural killer cell activity, and show several other immunomodulatory functions.
Indexing Annotation
English
:
"stimulators" or "inducers" =
INTERFERON INDUCERS
Pharmacological Action:
Antineoplastic Agents
Antiviral Agents
See Related
English
:
Receptors, Interferon
History Note
English
:
83; was INTERFERON 1963-82
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29469
Unique Identifier:
D007372
Occurrence in VHL
:
Similar:
DeCS