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Descriptor English:   STAT5 Transcription Factor 
Descriptor Spanish:   Factor de Transcripción STAT5 
Descriptor Portuguese:   Fator de Transcrição STAT5 
Synonyms English:   Factor, STAT5 Transcription
Mammary Gland Factor
Mammary Gland Specific Nuclear Factor
Mammary Gland-Specific Nuclear Factor
STAT5 Protein
STAT5a Protein
STAT5a Transcription Factor
STAT5alpha Protein
STAT5b Protein
STAT5b Transcription Factor
STAT5beta Protein
Signal Transducer and Activator of Transcription 5
Signal Transducer and Activator of Transcription 5A
Signal Transducer and Activator of Transcription 5B
Transcription Factor, STAT5
Transcription Factor, STAT5a
Transcription Factor, STAT5b  
Tree Number:   D12.644.360.024.342.500
Definition English:   A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA. 
History Note English:   2006(1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50798 
Unique Identifier:   D050799 

Occurrence in VHL: