Search on: CYCLINS 
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Descriptor English:   Cyclins 
Descriptor Spanish:   Ciclinas 
Descriptor Portuguese:   Ciclinas 
Synonyms English:   Cyclin  
Tree Number:   D12.644.360.262
D12.776.167.218
D12.776.476.262
Definition English:   A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators. 
Indexing Annotation English:   note specifics
See Related English:   Maturation-Promoting Factor
 
History Note English:   93; was CYCLIN 1991-2 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30942 
Unique Identifier:   D016213 

Occurrence in VHL: 		 

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