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DeCS
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Descriptor Inglés:
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Receptors, Death Domain
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Descriptor Español:
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Receptores de Muerte Celular
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Descriptor Portugués:
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Receptores de Morte Celular
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Sinónimos Inglés:
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DR Family Receptors
Death Domain Receptors
Death Receptors
Receptors, DR Family
Receptors, Death Domain Family
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Categoría:
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D12.776.543.750.690
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Definición Inglés:
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A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES. |
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Relacionados Inglés:
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Receptors, Tumor Necrosis Factor
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Nota Histórica Inglés:
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2007
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Calificadores Permitidos Inglés:
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Número del Registro:
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52336
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Identificador Único:
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D053218
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Ocurrencia en la BVS:
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Similar:
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DeCS
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