Descriptors Found: 1
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Descriptor English:   Zearalenone 
Descriptor Spanish:   Zearalenona 
Descriptor Portuguese:   Zearalenona 
Synonyms English:   F 2 Toxin
F-2 Toxin
F2 Toxin
Toxin, F-2
Toxin, F2  
Tree Number:   D02.455.426.559.389.657.852.900
Definition English:   (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. One of a group of compounds known under the general designation of resorcylic acid lactones. Cis, trans, dextro and levo forms have been isolated from the fungus Gibberella zeae (formerly Fusarium graminearum). They have estrogenic activity, cause toxicity in livestock as feed contaminant, and have been used as anabolic or estrogen substitutes. 
Indexing Annotation English:   a mycotoxin & non-steroidal estrogen; do not confuse with zearalanone (index under ZEARALENONE /analogs)
Pharmacological Action:   Estrogens, Non-Steroidal
History Note English:   91(75); was see under RESORCINOLS 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   15421 
Unique Identifier:   D015025 

Occurrence in VHL: