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DeCS
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Descriptor English:
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Transglutaminases
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Descriptor Spanish:
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Transglutaminasas
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Descriptor Portuguese:
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Transglutaminases
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Synonyms English:
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Gamma-Glutamyltransferases, Glutaminyl-Peptide
Glutaminyl Peptide Gamma Glutamyltransferases
Glutaminyl-Peptide Gamma-Glutamyltransferases
Protein Glutamine gamma Glutamyltransferases
Protein-Glutamine gamma-Glutamyltransferases
gamma-Glutamyltransferases, Protein-Glutamine
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Tree Number:
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D08.811.913.050.200.800
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Definition English:
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Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence. |
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Indexing Annotation English:
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distinguish X refs GLUTAMINYL-PEPTIDE GAMMA-GLUTAMYLTRANSFERASES and TRANSGLUTAMINASES from GAMMA-GLUTAMYL TRANSPEPTIDASE which is involved with glutathione metabolism; PLASMA TRANSGLUTAMINASE see FACTOR XIIIA is also available
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History Note English:
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2002(1986)
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Allowable Qualifiers English:
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Record Number:
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27787
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Unique Identifier:
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D011503
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Occurrence in VHL:
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Similar:
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DeCS
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