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DeCS
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Descriptor English:
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Angiopoietin-2
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Descriptor Spanish:
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Angiopoyetina 2
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Descriptor Portuguese:
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Angiopoietina-2
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Synonyms English:
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Angiopoietin 2
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Tree Number:
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D12.644.276.100.100.200
D12.776.467.100.100.200
D23.529.100.100.200
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Definition English:
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An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting. |
History Note English:
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2004; use ANGIOPOIETIN-2 (NM) 1997-2003
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Allowable Qualifiers English:
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Record Number:
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38239
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Unique Identifier:
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D042702
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Occurrence in VHL:
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Similar:
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DeCS
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