Pesquisa sobre: MFN=59212 
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Descritor Inglês:   Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase 
Descritor Espanhol:   Piruvato Deshidrogenasa Quinasa (Acetil-Transferidona) 
Descritor Português:   Quinase Piruvato Desidrogenase (Transferência de Acetil) 
Sinônimos Inglês:   Dehydrogenase Kinase, Pyruvate
Kinase, PDH
Kinase, Pyruvate Dehydrogenase
PDH Kinase
Pyruvate Dehydrogenase (Lipoamide) Kinase
Pyruvate Dehydrogenase Acetyl Transferring Kinase
Pyruvate Dehydrogenase Acetyl-Transferring Kinase
Pyruvate Dehydrogenase Kinase  
Categoria:   D08.811.913.696.620.682.700.783
Definição Inglês:   A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism. 
Nota Histórica Inglês:   2020(1972) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   59212 
Identificador Único:   D000081382 

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