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DeCS
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Descriptor English:
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T-Lymphoma Invasion and Metastasis-inducing Protein 1
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Descriptor Spanish:
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Proteína 1 de Invasión e Inducción de Metástasis del Linfoma-T
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Descriptor Portuguese:
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Proteína 1 Indutora de Invasão e Metástase de Linfoma de Células T
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Synonyms English:
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T Lymphoma Invasion and Metastasis inducing Protein 1
TIAM 1 Protein
TIAM-1 Protein
TIAM1 Protein
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Tree Number:
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D12.644.360.325.300.850
D12.776.476.325.300.850
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Definition English:
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A Rho guanine nucleotide exchange factor that consists of two pleckstrin homology domains flanking central Ras-binding, Dbl-homology (DH) and PDZ domains. It stimulates GTP-GDP exchange of rho-like GTPases such as RAC1 PROTEIN; CDC42 PROTEIN; and RHOA PROTEIN, and functions to link extracellular signals to remodeling of the CYTOSKELETON for CELL ADHESION and CELL MOVEMENT. |
See Related English:
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PDZ Domains
Pleckstrin Homology Domains
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57058
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Unique Identifier:
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D000075684
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Occurrence in VHL:
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Similar:
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DeCS
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