Search on: YOLK SAC TUMOR 
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Descriptor English:   Endodermal Sinus Tumor 
Descriptor Spanish:   Tumor del Seno Endodérmico 
Descriptor Portuguese:   Tumor do Seio Endodérmico 
Synonyms English:   Endodermal Sinus Tumors
Tumor, Endodermal Sinus
Tumor, Yolk Sac
Tumors, Endodermal Sinus
Tumors, Yolk Sac
Yolk Sac Tumor
Yolk Sac Tumors  
Tree Number:   C04.557.465.510.350
Definition English:   An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189) 
Indexing Annotation English:   coordinate with precoordinated organ/neoplasm term
History Note English:   94; was see MESONEPHROMA 1979-93; YOLK SAC TUMOR was see MESONEPHROMA 1979-93 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SC secondary SU surgery
TH therapy UL ultrastructure
UR urine VE veterinary
VI virology  
Record Number:   31487 
Unique Identifier:   D018240 

Occurrence in VHL: