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VENTURICIDINS
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DeCS
Descriptor
English
:
Venturicidins
Descriptor
Spanish
:
Venturicidinas
Descriptor
Portuguese
:
Venturicidinas
Tree Number:
D02.540.800
Definition
English
:
Toxic substances
isolated from various strains of
Streptomyces
. They are 20-membered
macrolides
that inhibit
oxidative phosphorylation
and mitochondrial ATPases.
Venturicidins
A and B are
glycosides
. Used mainly as tools in the study of mitochondrial function.
Indexing Annotation
English
:
uncoupling agents
& antifungal antibiotics; from
Streptomyces
Pharmacological Action:
Antifungal Agents
Uncoupling Agents
History Note
English
:
91(77); was see under LACTONES 1977-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
15103
Unique Identifier:
D014698
Occurrence in VHL
:
Similar:
DeCS