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BASILIXIMAB
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DeCS
Descriptor
English
:
Basiliximab
Descriptor
Spanish
:
Basiliximab
Descriptor
Portuguese
:
Basiliximab
Synonyms
English
:
CHI 621
SDZ CHI 621
Simulect
Tree Number:
D12.776.124.486.485.114.224.060.344
D12.776.124.790.651.114.224.060.407
D12.776.377.715.548.114.224.200.407
Definition
English
:
A chimeric murine-human monoclonal antibody that functions as an
INTERLEUKIN
2 RECEPTOR antagonist by binding to the alpha chain (CD25
ANTIGEN
) of the
interleukin-2
receptor on the surface of activated
T-LYMPHOCYTES
. It is used in the prevention of acute
graft rejection
episodes in
patients
undergoing renal
transplantation.
Pharmacological Action:
Immunosuppressive Agents
History Note
English
:
2019 (1998)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57677
Unique Identifier:
D000077552
Occurrence in VHL
:
Similar:
DeCS