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Descriptor English:   RNA Polymerase I 
Descriptor Spanish:   ARN Polimerasa I 
Descriptor Portuguese:   RNA Polimerase I 
Synonyms English:   DNA Dependent RNA Polymerase I
DNA-Dependent RNA Polymerase I
Polymerase A, RNA
Polymerase I, RNA
RNA Polymerase A  
Tree Number:   D08.811.913.696.445.735.270.750
Definition English:   A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin. 
History Note English:   84(77); was see under RNA POLYMERASES 1977-83 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   21057 
Unique Identifier:   D012318 

Occurrence in VHL: