Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   Mitogen-Activated Protein Kinase 1 
Descriptor Spanish:   Proteína Quinasa 1 Activada por Mitógenos 
Descriptor Portuguese:   Proteína Quinase 1 Ativada por Mitógeno 
Synonyms English:   Extracellular Signal Regulated Kinase 2
Extracellular Signal-Regulated Kinase 2
MAP Kinase 2
MAP Kinase, p42
MAPK1 Mitogen Activated Protein Kinase
MAPK1 Mitogen-Activated Protein Kinase
MAPK2 Mitogen Activated Protein Kinase
MAPK2 Mitogen-Activated Protein Kinase
Mitogen Activated Protein Kinase 1
Mitogen Activated Protein Kinase 2
Mitogen-Activated Protein Kinase 2
p42 MAP Kinase
p42 MAPK
p42(Mapk) Kinase
p42(Mitogen-Activated Protein Kinase)  
Tree Number:   D08.811.913.696.620.682.700.567.249.500
Definition English:   A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms. 
Indexing Annotation English:   Don't confuse MAP Kinase 2 with MAP KINASE KINASES referred to as MAP2 Kinases
History Note English:   2005(1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   33471 
Unique Identifier:   D019950 

Occurrence in VHL: