Search on:
HOMOHARRINGTONINE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Homoharringtonine
Descriptor
Spanish
:
Homoharringtonina
Descriptor
Portuguese
:
Mepesuccinato de Omacetaxina
Synonyms
English
:
Ceflatonin
Cephalotaxine
Homoharringtonine (3(R))-isomer
Omacetaxine
Omacetaxine Mepesuccinate
Synribo
Tree Number:
D03.132.420.500
D03.633.100.079.533.500
D03.633.400.624.500
Definition
English
:
Semisynthetic derivative of harringtonine that acts as a protein synthesis inhibitor and induces
APOPTOSIS
in tumor cells. It is used in the treatment of MYELOID
LEUKEMIA
, CHRONIC.
Pharmacological Action:
Antineoplastic Agents, Phytogenic
Protein Synthesis Inhibitors
History Note
English
:
2019 (1972)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
57767
Unique Identifier:
D000077863
Occurrence in VHL
:
Similar:
DeCS