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UROPORPHYRINOGENS
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DeCS
Descriptor
English
:
Uroporphyrinogens
Descriptor
Spanish
:
Uroporfirinógenos
Descriptor
Portuguese
:
Uroporfirinogênios
Synonyms
English
:
Uroporphyrinogen III
Tree Number:
D03.383.129.578.840.500.700.900
D03.633.400.909.500.700.900
D04.345.783.500.700.900
Definition
English
:
Porphyrinogens
which are intermediates in heme biosynthesis. They have four
acetic acid
and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl
methane
in the presence of
uroporphyrinogen III
cosynthetase and uroporphyrin I synthetase, respectively. They can yield
uroporphyrins
by autooxidation or
coproporphyrinogens
by
decarboxylation.
Indexing Annotation
English
:
porphyrins
History Note
English
:
91(76); was see under PORPHYRINOGENS 1976-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14979
Unique Identifier:
D014577
Occurrence in VHL
:
Similar:
DeCS