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CMC-544
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DeCS
Descriptor
English
:
Inotuzumab Ozogamicin
Descriptor
Spanish
:
Inotuzumab Ozogamicina
Descriptor
Portuguese
:
Inotuzumab Ozogamicina
Synonyms
English
:
Besponsa
CMC 544
CMC-544
CMC544
Tree Number:
D09.408.051.247.750
D12.776.124.486.485.114.224.060.794
D12.776.124.790.651.114.224.060.794
D12.776.377.715.548.114.224.200.794
Definition
English
:
Immunotoxin that consists of anti-CD22 (CD22
ANTIGEN
) humanized monoclonal antibody covalently linked to the antineoplastic antibiotic
CALICHEAMICIN
. It is used for the treatment of
adults
with relapsed or refractory B-cell precursor acute lymphoblastic
leukemia
(
LEUKEMIA
, ACUTE LYMPHOBLASTIC).
Pharmacological Action:
Antineoplastic Agents, Immunological
Antibiotics, Antineoplastic
Immunotoxins
History Note
English
:
2020 (2004)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
59131
Unique Identifier:
D000080045
Occurrence in VHL
:
Similar:
DeCS