Pesquisa sobre:
MFN=57101
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Deleted in Azoospermia 1 Protein
Descritor
Espanhol
:
Proteína 1 Delecionada en la Azoospermia
Descritor
Português
:
Proteína 1 Suprimida em Azoospermia
Sinônimos
Inglês
:
DAZ 1 Protein
DAZ-1 Protein
DAZ1 Protein
SPGY Protein
Categoria:
D12.776.157.725.813.375
D12.776.664.962.813.375
Definição
Inglês
:
An
RNA recognition motif
protein that is essential for
SPERMATOGENESIS
. It promotes entry of male
GERM CELLS
to
MEIOSIS
, possibly by regulating the translation of mRNAs. DAZ1 occurs within a cluster of
similar
genes on the
Y CHROMOSOME
that is prone to genetic deletions and duplications. Deletions in these genes, including DAZ1, are associated with
AZOOSPERMIA
and
OLIGOSPERMIA.
Relacionados
Inglês
:
RNA Recognition Motif
Nota Histórica
Inglês
:
2018
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
57101
Identificador Único:
D000075364
Ocorrência na BVS
:
Similar:
DeCS