Pesquisa sobre: MFN=57063 
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Descritor Inglês:   Serine Peptidase Inhibitor Kazal-Type 5 
Descritor Espanhol:   Inhibidor de Serinpeptidasas Tipo Kazal-5 
Descritor Português:   Inibidor de Serinopeptidase do Tipo Kazal 5 
Sinônimos Inglês:   Inhibitor, Lympho-Epithelial Kazal-Type
Kazal-Type Inhibitor, Lympho-Epithelial
LEKTI Protein
Lympho Epithelial Kazal Type Inhibitor
Lympho-Epithelial Kazal-Type Inhibitor
SPINK5 Protein
Serine Peptidase Inhibitor Kazal Type 5
Serine Protease Inhibitor Kazal Type 5
Serine Protease Inhibitor Kazal-Type 5  
Categoria:   D12.644.822.750.250
D12.776.645.688.250
Definição Inglês:   A secreted serine peptidase inhibitor that consists of 15 KAZAL MOTIFS and inhibits KALLIKREINS KLK5, KLK7, and KLK14 as well as TRYPSIN. It plays important roles in protecting MUCOSA against infection and inflammation, and in maintaining the integrity of the skin. Mutations in the SPINK5 gene are associated with NETHERTON SYNDROME. 
Relacionados Inglês:   Kazal Motifs
Netherton Syndrome
 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57063 
Identificador Único:   D000074163 

Ocorrência na BVS:
 

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