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DeCS
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Descritor Inglês:
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Cytokine TWEAK
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Descritor Espanhol:
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Citocina TWEAK
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Descritor Português:
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Citocina TWEAK
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Sinônimos Inglês:
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Apo3 Ligand
Cytokine, TWEAK
Ligand, Apo3
TNF Related Weak Inducer of Apoptosis
TNF-Related Weak Inducer of Apoptosis
TWEAK Cytokine
TWEAK, Cytokine
Tumor Necrosis Factor Ligand Superfamily Member 12
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Categoria:
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D12.644.276.374.750.155
D12.776.467.374.750.155
D23.529.374.750.155
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Definição Inglês:
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A proteolytically-cleaved membrane glycoprotein and member of the TNF superfamily that is highly expressed in a variety of tissues including heart, pancreas, brain, and peripheral blood lymphocytes. The secreted extracellular form is a weak inducer of APOPTOSIS for some cell types and a ligand for the FN14 RECEPTOR. It mediates activation of NF-KAPPA-B and promotes ANGIOGENESIS and proliferation of ENDOTHELIAL CELLS, as well as expression of cytokines involved in INFLAMMATION. |
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Nota Histórica Inglês:
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2018
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Qualificadores Permitidos Inglês:
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Número do Registro:
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57053
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Identificador Único:
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D000074049
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Ocorrência na BVS:
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Similar:
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DeCS
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