Pesquisa sobre: SIMEPREVIR 
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Descritor Inglês:   Simeprevir 
Descritor Espanhol:   Simeprevir 
Descritor Português:   Simeprevir 
Sinônimos Inglês:   435, TMC
435350, TMC
N-(17-(2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo(13.3.0.04,6)octadec-7-ene-4-carbonyl)(cyclopropyl)sulfonamide
Olysio
TMC 435
TMC 435350
TMC-435
TMC-435350
TMC435
TMC435350  
Categoria:   D02.886.590.700.700
D03.633.300.819
Definição Inglês:   Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS. 
Ação Farmacológica:   Antiviral Agents
Protease Inhibitors
 
Nota Histórica Inglês:   2016 (2008) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Número do Registro:   55903 
Identificador Único:   D000069616 

Ocorrência na BVS: 		 

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