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DeCS
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Descritor Inglês:
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Neuropilin-1
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Descritor Espanhol:
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Neuropilina-1
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Descritor Português:
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Neuropilina-1
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Sinônimos Inglês:
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A5 Antigen
Antigen, A5
NRP1 Protein
Neuropilin 1
Npn 1 Protein
Npn-1 Protein
Receptor, Sema III
Sema III Receptor
Semaphorin III Receptor
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Categoria:
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D12.776.543.750.590.500
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Definição Inglês:
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A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2. |
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Nota Histórica Inglês:
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2003; use NEUROPILIN-1 (NM) 1991-2002
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Qualificadores Permitidos Inglês:
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Número do Registro:
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37476
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Identificador Único:
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D039942
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Ocorrência na BVS:
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Similar:
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DeCS
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