Search on: TASIRNA 
Descriptors Found: 1
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Descriptor English:   RNA, Small Interfering 
Descriptor Spanish:   ARN Interferente Pequeño 
Descriptor Portuguese:   RNA Interferente Pequeno 
Synonyms English:   Hairpin RNA, Short
Hairpin RNA, Small
Interfering RNA, Short
Interfering RNA, Small
Piwi Interacting RNA
Piwi-Interacting RNA
RNA, Piwi Interacting
RNA, Piwi-Interacting
RNA, Scan
RNA, Short Hairpin
RNA, Short Interfering
RNA, Small Hairpin
RNA, Small Scan
Repeat Associated siRNA
Repeat-Associated siRNA
Scan RNA
Scan RNA, Small
Short Hairpin RNA
Short Interfering RNA
Small Hairpin RNA
Small Interfering RNA
Small Scan RNA
Trans Acting siRNA
Trans-Acting siRNA
piRNA
scnRNA
shRNA
siRNA
siRNA, Repeat Associated
siRNA, Repeat-Associated
siRNA, Trans Acting
siRNA, Trans-Acting
tasiRNA  
Tree Number:   D13.150.650.700
D13.444.735.150.700
D13.444.735.790.552.875
Definition English:   Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions. 
Indexing Annotation English:   Do not confuse with defective interfering RNA (diRNA), a viral RNA of DEFECTIVE VIRUSES.
See Related English:   MicroRNAs
RNA Interference
RNA-Induced Silencing Complex
 
History Note English:   2003; use RNA, SMALL INTERFERING (NM) 2001-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   37536 
Unique Identifier:   D034741 

Occurrence in VHL:
 

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