Search on: P160ROCK 
Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   rho-Associated Kinases 
Descriptor Spanish:   Quinasas Asociadas a rho 
Descriptor Portuguese:   Quinases Associadas a rho 
Synonyms English:   Coiled-Coil Kinase, rho-Associated
Protein Kinases, ROCK
ROCK I Protein Kinase
ROCK II Protein Kinase
ROCK Protein Kinases
ROCK-I Protein Kinase
ROCK-II Protein Kinase
ROK Kinase
p160 rhoA Binding Kinase ROKalpha
p160 rhoA-Binding Kinase ROKalpha
p160ROCK
rho Associated Coiled Coil Containing Protein Kinase 1
rho Associated Coiled Coil Containing Protein Kinase 2
rho Associated Coiled Coil Kinase
rho Associated Kinase
rho Associated Kinase 1
rho Associated Kinase 2
rho Associated Kinase alpha
rho Associated Kinase beta
rho Associated Kinases
rho Associated Protein Kinase alpha
rho Associated Protein Kinase beta
rho Kinase
rho-Associated Coiled-Coil Containing Protein Kinase 1
rho-Associated Coiled-Coil Containing Protein Kinase 2
rho-Associated Coiled-Coil Kinase
rho-Associated Kinase
rho-Associated Kinase 1
rho-Associated Kinase 2
rho-Associated Kinase alpha
rho-Associated Kinase beta
rho-Associated Protein Kinase alpha
rho-Associated Protein Kinase beta
rho-Kinase  
Tree Number:   D08.811.913.696.620.682.700.814
D12.644.360.590
D12.776.476.595
Definition English:   A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52746 
Unique Identifier:   D054460 

Occurrence in VHL:
 

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