Search on: P140-TRKA 
Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Receptor, trkA 
Descriptor Spanish:   Receptor trkA 
Descriptor Portuguese:   Receptor trkA 
Synonyms English:   NTRK1 Receptor
Neurotrophic Tyrosine Kinase Receptor Type 1
Proto Oncogene Products c trk
Proto Oncogene Protein trk
Proto-Oncogene Products c-trk
Proto-Oncogene Protein trk
Proto-Oncogene Protein, trk
Receptor, NTRK1
Receptor, Neurotrophic Tyrosine Kinase Type 1
c trk Protein
c-trk Protein
c-trk, Proto-Oncogene Products
c-trk, gp140
gp140 c trk
gp140 c-trk
gp140(c-TRK)
p140 trkA
p140-trkA
trk Proto Oncogene Protein
trk Proto-Oncogene Protein
trk, Proto-Oncogene Protein
trk1 Transforming Tryrosine Kinase
trkA Receptor  
Tree Number:   D08.811.913.696.620.682.725.400.660
D12.776.543.750.630.496
D12.776.543.750.750.400.550.550
Definition English:   A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis. 
History Note English:   2000; use RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE(NM) 1990-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   34455 
Unique Identifier:   D020917 

Occurrence in VHL:
 

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