Search on: P115RHOGEF 
Descriptors Found: 1
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Descriptor English:   Rho Guanine Nucleotide Exchange Factors 
Descriptor Spanish:   Factores de Intercambio de Guanina Nucleótido Rho 
Descriptor Portuguese:   Fatores de Troca de Nucleotídeo Guanina Rho 
Synonyms English:   ARHGEF1
Cool 1 Protein
Cool-1 Protein
PAK Interacting Exchange Factor beta
PAK-Interacting Exchange Factor beta
PIX Protein, beta
Protein, Cool-1
Protein, beta PIX
Protein, betaPIX
Rho Guanine Nucleotide Exchange Factor (GEF) 1
Rho Guanine Nucleotide Exchange Factor 6
Rho Guanine Nucleotide Exchange Factor 7
Rho Guanine Nucleotide Exchange Factor p115
RhoGEF
RhoGEF, p115
beta PIX Protein
betaPIX Protein
p115 RhoGEF
p115RhoGEF  
Tree Number:   D12.644.360.325.300.099
D12.776.476.325.300.099
Definition English:   Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55310 
Unique Identifier:   D064067 

Occurrence in VHL:
 

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