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OMEGA-AGA-IVA
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DeCS
Descriptor
English
:
omega-Agatoxin IVA
Descriptor
Spanish
:
omega-Agatoxina IVA
Descriptor
Portuguese
:
ômega-Agatoxina IVA
Synonyms
English
:
IVA, omega-Agatoxin
omega Aga IVA
omega Agatoxin IVA
omega-Aga-IVA
Tree Number:
D12.644.400.562
D12.776.093.249.500
D20.888.065.870.324.500
D23.946.833.065.870.324.500
Definition
English
:
A
neuropeptide
toxin from the venom of the funnel web
spider
, Agelenopsis aperta. It inhibits
CALCIUM CHANNELS
, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits
CALCIUM CHANNELS
, Q-TYPE.
Pharmacological Action:
Calcium Channel Blockers
Neurotoxins
History Note
English
:
2000; use OMEGA-AGATOXIN IVA (NM) 1992-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
EN
enzymology
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
34517
Unique Identifier:
D020867
Occurrence in VHL
:
Similar:
DeCS