Search on: MFN=59202 
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Descriptor English:   Protein-Arginine Deiminase Type 1 
Descriptor Spanish:   Arginina Deiminasa Proteína-Tipo 1 
Descriptor Portuguese:   Proteína-Arginina Desiminase do Tipo 1 
Synonyms English:   PAD Type I
PADI1 Protein
Peptidyl Arginine Deiminase Type 1
Peptidyl Arginine Deiminase Type I
Peptidylarginine Deiminase I
Peptidylarginine Deiminase Type 1
Peptidylarginine Deiminase Type I
Protein Arginine Deiminase 1
Protein Arginine Deiminase Type 1
Protein Arginine Deiminase Type I
Protein-Arginine Deiminase Type I  
Tree Number:   D08.811.277.721.250
Definition English:   A peptidylarginine deiminase isoenzyme. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. It functions within the epidermis, targeting INTERMEDIATE FILAMENTS; KERATINS; and filaggrin for CITRULLINATION to promote epidermal cornification. 
See Related English:   Citrullination
 
History Note English:   2020 (1999) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   59202 
Unique Identifier:   D000080062 

Occurrence in VHL:
 

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DeCS