Search on: MFN=59187 
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 1 / 1 DeCS     
Descriptor English:   Parthanatos 
Descriptor Spanish:   Parthanatos 
Descriptor Portuguese:   Parthanatos 
Synonyms English:   Cell Death, PARP-1-Dependent
Cell Death, PARP-Dependent
PARP 1 Dependent Cell Death
PARP Dependent Cell Death
PARP-1-Dependent Cell Death
PARP-Dependent Cell Death  
Tree Number:   G04.146.954.750
Definition English:   A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation. 
History Note English:   2020 
Allowable Qualifiers English:  
DE drug effects GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   59187 
Unique Identifier:   D000079323 

Occurrence in VHL: 		 

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DeCS