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DeCS
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Descriptor English:
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Hot Melt Extrusion Technology
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Descriptor Spanish:
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Tecnología de Extrusión de Fusión en Caliente
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Descriptor Portuguese:
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Tecnologia de Extrusão por Fusão a Quente
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Synonyms English:
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Hot Melt Extrusion
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Tree Number:
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E05.916.840
J01.897.360.500
J01.897.836.500
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Definition English:
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Solvent-free method for preparing numerous types of drug delivery systems and dosage forms for active pharmaceutical ingredients that have solubility issues. It involves pumping polymeric materials at temperatures above their glass transition temperature to mix in active pharmaceutical ingredients with or without binders thus forming an amorphous product with an increase in the dissolution profile for the active pharmaceutical ingredients. |
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History Note English:
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2020
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Allowable Qualifiers English:
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Record Number:
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59125
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Unique Identifier:
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D000080048
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Occurrence in VHL:
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Similar:
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DeCS
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