Search on: MFN=59042 
Descriptors Found: 1
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Descriptor English:   Brentuximab Vedotin 
Descriptor Spanish:   Brentuximab Vedotina 
Descriptor Portuguese:   Brentuximab Vedotin 
Synonyms English:   Adcetris
CAC10 1006
CAC10-1006
CAC101006
SGN 35
SGN-35
SGN35
cAC10 vcMMAE
cAC10-vcMMAE
cAC10vcMMAE  
Tree Number:   D12.644.456.217
D12.776.124.486.485.114.224.060.438
D12.776.124.790.651.114.224.060.469
D12.776.377.715.548.114.224.200.469
Definition English:   Immunoconjugate that consists of the chimeric monoclonal anti - CD30 ANTIGEN antibody cAC-10 conjugated to monomethyl auristatin E. It is used for the treatment of LYMPHOMA. 
Pharmacological Action:   Antineoplastic Agents, Immunological
Immunotoxins
 
History Note English:   2020 (2010) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   59042 
Unique Identifier:   D000079963 

Occurrence in VHL:
 

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