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MFN=59015
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DeCS
Descriptor
English
:
Ado-Trastuzumab Emtansine
Descriptor
Spanish
:
Ado-Trastuzumab Emtansina
Descriptor
Portuguese
:
Ado-Trastuzumab Emtansina
Synonyms
English
:
Ado Trastuzumab Emtansine
Kadcyla
Trastuzumab DM1
Trastuzumab DM1 Conjugate
Trastuzumab Emtansine
Trastuzumab-DM1
Trastuzumab-DM1 Conjugate
huN901 DM1
huN901-DM1
huN901DM1
Tree Number:
D02.540.505.495.500
D04.345.295.500.500
D12.776.124.486.485.114.224.060.875.500
D12.776.124.790.651.114.224.060.875.500
D12.776.377.715.548.114.224.200.875.500
Definition
English
:
Immunotoxin that consists of humanized monoclonal anti-HER2 antibody
TRASTUZUMAB
covalently linked to anti-microtubule agent MAYTANSINOID DM1 for treatment of metastatic
breast
cancer in
patients
who previously received
trastuzumab
and a
TAXANES
, separately or in combination.
Pharmacological Action:
Antineoplastic Agents, Immunological
Immunotoxins
Tubulin Modulators
History Note
English
:
2020 (2010)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
59015
Unique Identifier:
D000080044
Occurrence in VHL
:
Similar:
DeCS