Search on: MFN=56998 
Descriptors Found: 1
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Descriptor English:   Copper-Transporting ATPases 
Descriptor Spanish:   ATPasas Transportadoras de Cobre 
Descriptor Portuguese:   ATPases Transportadoras de Cobre 
Synonyms English:   ATP7A Protein
ATP7B Cu Binding P Type ATPase
ATP7B Cu-Binding P Type ATPase
ATPase 1, Copper-Transporting
ATPase 2, Copper-Transporting
ATPase Copper Transporting alpha
ATPase, Copper-Transporting
ATPase, Cu++ Transporting, beta Polypeptide (Wilson Disease)
ATPase, Pineal Night-Specific
ATPases, Copper-Transporting
ATPases, Cu-Transporting
Adenosine Triphosphatases, Copper-Transporting
Copper Pump 1
Copper Transporting ATPase
Copper Transporting ATPase 1
Copper Transporting ATPase 2
Copper Transporting ATPases
Copper Transporting Adenosine Triphosphatases
Copper-Transporting ATPase
Copper-Transporting ATPase 1
Copper-Transporting ATPase 2
Copper-Transporting Adenosine Triphosphatases
Cu Transporting ATPases
Cu(+)-Transporting ATPases
Cu-Transporting ATPases
Menkes Disease Associated Protein
Menkes Disease-Associated Protein
Night-Specific ATPase, Pineal
PINA Enzyme
Pineal Night Specific ATPase
Pineal Night-Specific ATPase
Triphosphatases, Copper-Transporting Adenosine
Wilson Disease Cu Binding P Type ATPase
Wilson Disease Cu-Binding P Type ATPase
Wilson Disease Protein  
Tree Number:   D08.811.277.040.025.314.500
D12.776.157.530.450.250.578.750
D12.776.157.530.813.500
D12.776.543.585.450.250.578.750
D12.776.543.585.813.500
Definition English:   P-type ATPases which transport copper ions across membranes in prokaryotic and eukaryotic cells. They possess a conserved CYSTEINE-HISTIDINE-SERINE (CPx) amino acid motif within their transmembrane helices that functions in cation translocation and catalytic activation, and an N-terminal copper-binding CxxC motif that regulates enzyme activity. They play essential roles in intracellular copper homeostasis through regulating the uptake, efflux and storage of copper ions, and in cuproprotein biosynthesis. 
See Related English:   Hepatolenticular Degeneration
Menkes Kinky Hair Syndrome
 
History Note English:   2018 (1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56998 
Unique Identifier:   D000073840 

Occurrence in VHL:
 

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DeCS