Search on: GAMMA-SYNUCLEIN 
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Descriptor English:   gamma-Synuclein 
Descriptor Spanish:   gamma-Sinucleína 
Descriptor Portuguese:   gama-Sinucleína 
Synonyms English:   Persyn
Synoretin
gamma Synuclein  
Tree Number:   D12.776.631.860.750
Definition English:   A homolog of ALPHA-SYNUCLEIN that plays a role in neurofilament network integrity. It is overexpressed in a variety of human NEOPLASMS and may be involved in modulating AXON architecture during EMBRYONIC DEVELOPMENT and in the adult. Gamma-Synuclein may also activate SIGNAL TRANSDUCTION PATHWAYS associated with ETS-DOMAIN PROTEIN ELK-1. 
History Note English:   2006(1988) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51168 
Unique Identifier:   D051845 

Occurrence in VHL: 		 

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