Search on: D-METHORPHAN 
Descriptors Found: 1
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Descriptor English:   Dextromethorphan 
Descriptor Spanish:   Dextrometorfano 
Descriptor Portuguese:   Dextrometorfano 
Synonyms English:   Delsym
Dextromethorphan Hydrobromide
Dextromethorphan Hydrobromide, (+-)-Isomer
Dextromethorphan Hydrobromide, Monohydrate
Dextromethorphan Hydrochloride
Dextromethorphan, (+-)-Isomer
Hydrobromide, Dextromethorphan
Hydrochloride, Dextromethorphan
Levomethorphan
Racemethorphan
d-Methorphan
l-Methorphan  
Tree Number:   D03.132.577.249.200
D03.605.497.212
D03.633.400.686.212
D04.615.723.795.200
Definition English:   Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity. 
Pharmacological Action:   Antitussive Agents
Excitatory Amino Acid Antagonists
 
History Note English:   91(72); was see under LEVORPHANOL 1972-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   3936 
Unique Identifier:   D003915 

Occurrence in VHL:
 

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DeCS