Search on: BETA-MANNOSIDASE 
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Descriptor English:   beta-Mannosidase 
Descriptor Spanish:   beta-Manosidasa 
Descriptor Portuguese:   beta-Manosidase 
Synonyms English:   beta D Mannosidase
beta Mannanase
beta Mannosidase
beta-D-Mannosidase
beta-Mannanase
manA protein (beta-Mannosidase)  
Tree Number:   D08.811.277.450.625.750
Definition English:   An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS. 
Indexing Annotation English:   /defic: consider also BETA-MANNOSIDOSIS
See Related English:   beta-Mannosidosis
 
History Note English:   2004; use BETA-MANNOSIDASE (NM) 1980-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38164 
Unique Identifier:   D044902 

Occurrence in VHL:
 

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