Search on: VEMURAFENIB 
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Descriptor English:   Vemurafenib 
Descriptor Spanish:   Vemurafenib 
Descriptor Portuguese:   Vemurafenib 
Synonyms English:   PLX 4032
PLX4032
R05185426
RG 7204
RG-7204
RG7204
Zelboraf  
Tree Number:   D02.065.884.919
D02.886.590.700.919
D03.633.100.473.936
Definition English:   An indole sulfonamide compound and inhibitor of BRAF KINASES that is used for the treatment of unresectable or metastatic MELANOMA. 
Pharmacological Action:   Antineoplastic Agents
Protein Kinase Inhibitors
 
History Note English:   2019 (2010) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   57657 
Unique Identifier:   D000077484 

Occurrence in VHL:
 

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