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DeCS
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Descriptor English:
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Vascular Endothelial Growth Factor Receptor-1
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Descriptor Spanish:
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Receptor 1 de Factores de Crecimiento Endotelial Vascular
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Descriptor Portuguese:
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Receptor 1 de Fatores de Crescimento do Endotélio Vascular
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Synonyms English:
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FLT VEGF Receptor
FLT1 RTK
FLT1 Receptor Tyrosine Kinase
Proto Oncogene Protein flt
Proto-Oncogene Protein flt
Receptor, FLT VEGF
Tyrosine Kinase, fms-Like
VEGF Receptor flt 1 Protein
VEGF Receptor flt-1 Protein
VEGF Receptor, FLT
VEGFR-1
Vascular Endothelial Growth Factor Receptor 1
fms-Like Tyrosine Kinase
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Tree Number:
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D08.811.913.696.620.682.725.400.950.100
D12.776.543.750.630.750.100
D12.776.543.750.750.400.910.100
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Definition English:
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A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction. |
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History Note English:
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2003; use VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 (NM) 1990-2002; for FLK-1 RECEPTOR TYROSINE KINASE use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1993-2002
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Allowable Qualifiers English:
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Record Number:
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37358
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Unique Identifier:
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D040281
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Occurrence in VHL:
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Similar:
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DeCS
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