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TUFTSIN
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DeCS
Descriptor
English
:
Tuftsin
Descriptor
Spanish
:
Tuftsina
Descriptor
Portuguese
:
Tuftsina
Synonyms
English
:
L-Thr-L-Lys-L-Pro-L-Arg
L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine
Taftsin
Tree Number:
D12.644.456.840
D12.644.541.500.650.750
D12.776.124.486.485.397.500
D12.776.124.486.485.680.650.750
D12.776.124.790.651.397.500
D12.776.124.790.651.680.650.750
D12.776.377.715.548.397.500
D12.776.377.715.548.680.650.750
Definition
English
:
N(2)-((1-(N(2)-L-Threonyl)-L-lysyl)-L-prolyl)-L-arginine. A tetrapeptide produced in the
spleen
by enzymatic cleavage of a leukophilic gamma-globulin. It stimulates the phagocytic activity of blood polymorphonuclear
leukocytes
and
neutrophils
in particular. The peptide is located in the Fd fragment of the gamma-globulin molecule.
Pharmacological Action:
Immunologic Factors
History Note
English
:
84(75); was see under IMMUNOGLOBULINS, FD 1975-83; LEUKOKININ (with LEUCOKININ a see ref to it) was see under GAMMA GLOBULINS 1975-83; LEUKOKININ & LEUCOKININ were see TUFTSIN 1984-93
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
14807
Unique Identifier:
D014405
Occurrence in VHL
:
Similar:
DeCS