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DeCS
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Descriptor English:
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Trans-Splicing
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Descriptor Spanish:
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Trans-Empalme
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Descriptor Portuguese:
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Trans-Splicing
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Synonyms English:
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RNA Splicing, Trans
RNA Trans Splicing
RNA Trans-Splicing
Splicing, Trans
Trans RNA Splicing
Trans Splicing
Trans-Splicings, RNA
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Tree Number:
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G02.111.760.700.750
G03.839.700.750
G05.308.700.700.750
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Definition English:
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The joining of RNA from two different genes. One type of trans-splicing is the "spliced leader" type (primarily found in protozoans such as trypanosomes and in lower invertebrates such as nematodes) which results in the addition of a capped, noncoding, spliced leader sequence to the 5' end of mRNAs. Another type of trans-splicing is the "discontinuous group II introns" type (found in plant/algal chloroplasts and plant mitochondria) which results in the joining of two independently transcribed coding sequences. Both are mechanistically similar to conventional nuclear pre-mRNA cis-splicing. Mammalian cells are also capable of trans-splicing. |
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Indexing Annotation English:
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note category: a physiol process taking place within the cell nucleus; do not confuse with DNA, RECOMBINANT; CLONING, MOLECULAR; or GENETIC ENGINEERING
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See Related English:
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RNA, Spliced Leader
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History Note English:
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99
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Allowable Qualifiers English:
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Record Number:
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33898
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Unique Identifier:
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D020040
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Occurrence in VHL:
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Similar:
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DeCS
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