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STAUROSPORINE
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DeCS
Descriptor
English
:
Staurosporine
Descriptor
Spanish
:
Estaurosporina
Descriptor
Portuguese
:
Estaurosporina
Synonyms
English
:
8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
Tree Number:
D03.132.436.750
D03.633.100.473.144.750
D03.633.100.473.402.750
D03.633.300.148.750
Definition
English
:
An indolocarbazole that is a potent
PROTEIN KINASE C
inhibitor which enhances cAMP-mediated responses in human
neuroblastoma
cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Pharmacological Action:
Enzyme Inhibitors
History Note
English
:
97; was STAUROSPORINE (NM) 1977-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
32990
Unique Identifier:
D019311
Occurrence in VHL
:
Similar:
DeCS