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DeCS
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Descriptor English:
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Sorafenib
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Descriptor Spanish:
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Sorafenib
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Descriptor Portuguese:
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Sorafenibe
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Synonyms English:
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4-(4-(3-(4-Chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxylic acid methyamide-4-methylbenzenesulfonate
BAY 43 9006
BAY 43-9006
BAY 439006
BAY 545 9085
BAY 545-9085
BAY 5459085
BAY 673472
BAY-545-9085
BAY-673472
BAY5459085
Nexavar
Sorafenib N Oxide
Sorafenib N-Oxide
Sorafenib Tosylate
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Tree Number:
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D02.455.426.559.389.703.757
D02.948.681.757
D03.066.515.530.750
D03.383.725.547.530.750
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Definition English:
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A niacinamide and phenylurea derivative that inhibits multiple intracellular and cell surface kinases thought to be involved in ANGIOGENESIS, including RAF KINASES and VEGF RECEPTORS. It is used in the treatment of advanced RENAL CELL CARCINOMA and HEPATOCELLULAR CARCINOMA, and for treatment of THYROID CARCINOMA refractory to radioactive iodine therapy. |
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Pharmacological Action:
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Antineoplastic Agents
Protein Kinase Inhibitors
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History Note English:
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2019 (2003)
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Allowable Qualifiers English:
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Record Number:
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57527
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Unique Identifier:
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D000077157
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Occurrence in VHL:
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Similar:
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DeCS
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